What Is The Difference Between CBD And CBDA?

What Is The Difference Between CBD And CBDA?

You are just about to read about CBD, and then you also come across CBDA and continue reading. You may begin to wonder, is there anything that makes CBDA better than CBD? In the first place, what is CBDA? What are the benefits of CBDA? These questions and many other points will be covered in

You are just about to read about CBD, and then you also come across CBDA and continue reading. You may begin to wonder, is there anything that makes CBDA better than CBD? In the first place, what is CBDA? What are the benefits of CBDA? These questions and many other points will be covered in this article. This article contains the complete information you need about CBD and CBDA.

First, let us begin by talking about what CBDA means.

CBD Vs. CBDA – What is The Difference?

Most people have asked, what is CBDA? Cannabidiolic acid, which is generally known as CBDA, is one of the compounds that can be found in the Cannabinoid (hemp). On the other hand, Cannabidiol, which is generally known as CBD, is another type of compound that can be found in the Cannabinoid. However, if you thoroughly examine a fresh Cannabinoid, you will only see a small quantity of CBD. While you keep monitoring the fresh Cannabinoid, you will notice that there is an abundance of CBDA in it.

There is a reason why you will come across a small quantity of CBD and find a large amount of CBDA in the Cannabinoid. The idea is that the Cannabidiolic acid serves as the acid forerunner of the Cannabidiol. This means that the CBD comes into existence only when there is a heating of the raw Cannabinoid, which contains CBDA (Cannabidiolic acid). When the natural hemp is heated, it will result in a decarboxylation. Decarboxylation is a scientific term that refers to the removal of a carboxyl group.

There was a belief sometime ago that raw hemp cannot provide a curative effect if the CBDA has not been transformed into CBD after it has been heated. The truth is that scientists have carried out more research on CBDA, comparing it to CBD. Now, let us talk about how CBDA affects the body.

The Effects of CBDA on the Body

More research about the health benefits of hemp is still ongoing. But right now, it is as if the CBDA and CBD share a few things in common. Both the CBD and the CBDA do not make humans intoxicated or ‘high.’ The reason is that they do not have direct interactions with the endocannabinoid system receptors in our body.

Generally, most of the effects being caused on our body by the CBDA and CBD are triggered by the activation of the 5HT1A serotonin receptors. The serotonin receptor is a kind of substance in the brain/body that carries a signal from one nerve cell to another. The serotonin receptors have the responsibility of regulating sleep, mood, nausea, feelings, and anxiety.

To test the CBD, individuals facing social anxiety were being given the Cannabidiol, and these people have improved in the aspect of speaking publicly. The research made on CBDA about depression is still in a stage before clinical testing. But, research has proven that CBDA evokes an antidepressant effect on a rat at 10-99 times lower than the Cannabidiol (CBD). The mood-boosting and anti-anxiety effects of the CBDA are due to the increased level of serotonin.

The activation of the serotonin receptors (5HT1A) has also resulted in the investigation of the CBDA as a future drug for nausea. One study has found that CBDA reduces nausea more than CBD.

CBDA is also a dosage against inflammation, just like the CBD. It possesses vital mediators of inflammation, which are COX-1 enzyme and COX-2 enzyme.

Current CBDA research conducted

A lot of research has been made about the cannabis plant (hemp). As we are speaking, the effects which CBDA has on the body have not yet been examined on a human. But, at a level before the clinical test, many exciting studies have been done. Therefore, this means that the effects of CBDA were examined on animal models or cell cultures. So, we can say that there is no actual conclusion about the health benefits of CBDA until research is carried out in humans.

What we know for sure is that the research giants of Cannabinoid currently have clear proof that CBDA is a potential drug for epilepsy. Acting as the world leaders in the treatment of epilepsy with Cannabinoid, the research giants have something else about CBDA. They discover that the bioavailability of CBDA is better than the CBD, resulting in a very rapid and quick result. They also noticed that less quantity of CBDA is needed to achieve a curative effect compared to the CBD.

Studies have also been made on CBDA about its activity of preventing tumors. Scientists found that CBDA can help in preventing cancer cells from migrating in certain cancer lines (breast).

Now, let us talk about the Cannabidiol (CBD) before proceeding to CBDA vs. CBD.

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Cannabidiol (CBD) – What is it?

Cannabidiol, which we have mentioned earlier, is generally known as CBD. CBD is one of the active compounds that are found in cannabis, which is usually known as hemp. As a vital component of hemp, CBD is gotten directly from the cannabis (hemp) plant, which is also related to marijuana. Even though CBD is a component found in marijuana, it does not make a person ‘high’. World Health Organization claims that there is no effect of CBD abuse or has CBD caused any health problems.

How Cannabidiol (CBD) works in the body

Medical reports have claimed that there are two receivers of Cannabinoid in the endocannabinoid system in the body.  These receivers are CB1, and as well CB2.

The part of the brain responsible for regulating some specific feelings like mood, memory, thinking, and appetite is where the CB1 receivers can be found while the second one, which is the CB2 receiver, is located in the system, which is capable of fighting against any form of disease. This means that the body will eventually have the ability to recover from inflammation and chronic pain.

THC is being attached to the receivers of CBD. This is done not in a direct way, but by making the body more enticed to deal with its Cannabinoid. Then pain and inflammation will be reduced from a person’s body.

Has Cannabidiol (CBD) been legalized?

Although the legalization of Cannabidiol (CBD) is still fluctuating, it can yet be obtained in various areas of the US (United States). In the 50 states, specific laws are guiding the legalization of CBD, all having their restrictions. As for the federal government, they still view CBD just as marijuana, but that does not mean that they kick against it habitually.

Some years back, the requirements were eased by the FDA, which has allowed researchers to carry out some trials regarding CBD. In recent years, CBD has been gotten online by a lot of people without any medical license of cannabis. The position of government about CBD is where the CBD came from. Either it came from marijuana, or it is being derived from hemp.

There are some changes expected on the legalization of CBD. Currently, there is a work in progress that will help in making Cannabis plant legal and make it hard to ban.

The health benefits of Cannabidiol (CBD)

People have talked about the evidence of CBD to be very good because of the many health problems it treats. One strong evidence of CBD’s capability in handling severe health problems is how effective it is in treating some cruel syndromes of epilepsy in children. Some of the syndromes which it addresses are the Lennox-Gastaut and Dravet syndrome. These syndromes hardly respond to medications of seizure. Many research shows that CBD has been able to reduce a large number of seizures, even stopping them.

Right now, some videos have been posted on the internet about the effect of CBD on the children who are now free from their seizures. These videos can now be viewed. FDA has res recently approved a medicine derived from cannabis containing CBD.

CBD is used commonly for the reduction of anxiety and is also used for patients dealing with insomnia. Recent studies have suggested that CBD can help a person fall asleep, so can it also help a person stay awake.

Chronic pains can be handled and treated with the use of CBD. Studies have shown that the application of CBD on the skin can help with the reduction of pain and inflammation caused by arthritis. Another research also shows the process by which CBD is hindering inflammation and neuropathic pain. These two pains just mentioned are tough to treat. Most of these studies are made with animal models, but more studies will be made with humans to prove that CBD can control pain.

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Is Cannabidiol (CBD) Safe for Consumption?

There might be some side effects of consuming CBD. These side effects are fatigue, irritability, and nausea.

CBD brings about the increment of the blood level in the blood Coumadin. It can also help in increasing the level of some medications you are taking just the way a grapefruit juice increases medications. One significant thing that marks CBD safe is it being sold and recommended as a supplement and not medicine. Now, there is no regulation of the safety of supplements (dietary) by the FDA. There might not be any certainty about the most effective dosage of Cannabidiol for a particular health condition.

To summarize it all, Cannabidiol (CBD), is as good as safe for consumption even if there might be little side effects.

CBDA Benefits

Remember what we talked about earlier on CBDA, which stands for Cannabidiolic acid. To refresh our memories, let us explain briefly what CBDA is and what brings about CBD.

We have mentioned that CBDA is a type of chemical compound that is found in a raw Cannabinoid plant, still known as a hemp plant. When we talk about a raw hemp plant, we are referring to a plant that has not yet been heated and has not been processed. We also mentioned from the beginning of this article that it serves as the acid forerunner of the Cannabidiol (CBD).

There is an estimation that more than 94 percent of Cannabinoid in a fresh hemp plant comes as THCA, which means “tetrahydrocannabinolic acid.” Then, the remaining percent is present as CBDA. The question arises again: what benefits does the CBDA have?

Still, have it in mind that CBD comes into existence only when the CBDA has been heated. There are still lots of things to be learned about CBDA. Notwithstanding, a lot of people have discovered the curative or health benefits of consuming CBDA.  Now, let us focus on the CBDA benefits, and we will also talk about specific health problems that can be treated with CBDA.

Health benefits of CBDA

CBDA has a lot of health benefits, and it has been confirmed that there are some properties that CBDA has. Below are the curative properties.

CBDA is anti-proliferative, it has an antioxidant property, it is anti-inflammatory, It serves as an anti-bacteria, It is antimicrobial, Analgesic, Anti-nausea

Health problems that can be treated with CBDA

All the health problems that can be treated with CBD can as well be treated with CBDA. As we mentioned earlier, less quantity of CBDA is needed to achieve a curative effect compared to the CBD. This depends on the health condition that needs to be taken care of. The research that has been made on CBDA is still little. Most of the investigations on Cannabinoid is about CBD. Let us get on by talking about the conditions that can be handled with CBDA one after the other.


CBDA has an anti-nausea effect on the body. This anti-nausea effect it has was discovered through a study back in 2012. The study was being conducted on rodents, i.e. rats. The result of the study showed the effectiveness of CBDA in relieving or reducing nausea more than CBDCBDA triggers the activation of the 5HT1A serotonin receptors, which plays a role both in vomiting and nausea.

Psychotic disorder and anxiety

Much research has not yet been done about how CBDA treats psychotic disorders and also anxiety. However, the world leaders in the treatment of epilepsy with Cannabinoid have clear proof that CBDA can effectively treat these disorders.

Arthritis and inflammation

No study has been made yet to know if CBDA can effectively treat inflammation and arthritis. Nevertheless, cell cultures have been examined in the laboratory, and the result shows that CBDA can treat inflammation like NSAID.

The NSAID is a drug for treating inflammations. People who are suffering from arthritis take this drug in a specific amount. One thing you should know about taking NSAID is that it has significant side effects. Some of the problems that might come from consuming NSAID are high BP, headaches, stomach ulcers, hemorrhage, and kidney damage.

Research has shown that CBDA can effectively treat arthritis and inflammation because of its interaction with COX-2. Anti-inflammatory drugs go mainly to the COX-2, and so, making the effects possible.


There have not been any experiments on humans about the effects CBDA has on cancer. But, many have been carried out on cell lines and animals. The result of the experiment shows that both CBD and CBDA have very practical properties of anticancer. In the year 2012, it was discovered that CBDA’s anticancer effect was seen in breast cancer. Through experiments, researchers determined three factors which are:

  • CBDA slows down the migration of a solid breast cancer cell.
  • RhoA needs to be activated before the mechanism of CBDA can be effective
  • RhoA slows down the mobility of cancer cells.

As we have talked about the health benefits of CBDA, let us also talk about what CBD can be used for and the benefits associated with it.

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We have already explained what CBD is from the beginning of this article. Now, let us move ahead to CBD oil and the health benefits it has.

In a straightforward manner, CBD oil is produced by the extraction of Cannabidiol from a fresh hemp plant, and then, diluting or contaminating it with oil. You can dilute the CBD either with the oil of hemp seed or coconut oil. It has been confirmed by scientists that CBD oil can help in the reduction of anxiety and severe pain.

Here are some of the health benefits of CBD oil that have been confirmed by scientific studies.

Pain reliever

Since the year 2900 B.C to date, marijuana has been the antidote for pain. Recently, scientific research has pointed out some components in hemp, including Cannabidiol, which plays a role in relieving pain.

According to scientific research, Cannabidiol (CBD) can help in reducing severe pain by reducing inflammation. Its interaction with neurotransmitters can also help to alleviate acute pain.

In summation, the combination of CBD and THC may be beneficial in relieving severe pain and other diseases that cause chronic pain. Conditions like arthritis and multiple sclerosis.

Reduction of depression and anxiety

These two problems affect mental health and can seriously have negative impacts on a person’s well-being. World Health Organization claims that depression is among the causes of disability in humans.

The problems mentioned above are often being treated using pharmaceutical drugs, which results in some inevitable side effects. Using pharmaceutical drugs to treat anxiety and depression can cause agitation, headache, insomnia, drowsiness, and also sexual dysfunction.

CBD oil has been able to treat anxiety and depression effectively. This has made a large number of people with these health problems turn to use natural CBD oil.

To summarize it all, the oil of CBD can reduce both anxiety and depression.

Reduction of Acne

Acne is one skin problem that is common to people. Up to 10 percent of the world’s population is being affected by acne.

Some of the things that cause acne are bacteria, genetics, oily secretion, and many more. Just as we have said earlier about the anti-bacterial properties of Cannabidiol, CBD oil can be able to treat acne. It can also reduce the production of sebum effectively.

In summary, CBD is very beneficial to the skin because of its anti-inflammatory and anti-bacterial properties.

Beneficial to the heart

Research has pointed out a lot of benefits that CBD has on the heart, which includes its power in reducing high BP (Blood Pressure).

High BP can cause various heart diseases, which can include stroke, metabolic syndrome, and also heart attack.

Scientific studies have shown that CBD can work to protect the heart from various heart conditions. In addition to that, CBD helps to reduce the death of the cell and also inflammation, which can cause heart disease.

To summarize it and make it simple, CBD can reduce blood pressure. It also can protect the heart from any damage.

CBD has Neuroprotective Properties

One study about CBD shows its ability to treat neurological disorders such as multiple sclerosis and epileptic seizure. Research has also shown that many other forms of neurological diseases can be treated with CBD.

CBD can ease the symptoms of Parkinson’s disease, Alzheimer’s disease, epilepsy, convulsions, fatigue, fever, and many more neurological problems.

CBD can reduce the symptoms of cancer

It is very effective in reducing the symptoms of cancer. It also helps to reduce the side effects that have been caused by the treatment of cancer, such as pain, nausea, and vomiting.

A study showed that widespread breast cancer cells had been reduced by CBD.

What we are saying, in essence, is that CBD has anti-cancer properties that help in reducing and treating cancer. Additionally, click here to learn about CBD and Crohn’s Disease!

CBD Vs. CBDA. We hope this article has helped you know the difference between these two compounds in the cannabis plant. You have also learned about their various benefits.

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The Federal Food, Drug and Cosmetic Act requires this disclaimer. We collected this information from various sources for the convenience of our customers. The Food and Drug Administration did not evaluate the statements regarding these products. FDA research did not confirm the efficacy of these products yet. These products are not to diagnose, treat, cure, or prevent any disease. The information we present here’s not a substitute for information from health care practitioners. It is also not an alternative to information from health care practitioners. Before using any product, you should consult your doctor and ask about the risk of interactions or complications.

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